Tag Archives: crucial

Faulty manufacturing trips up Nektar’s Bristol-partnered cancer drug in crucial trial

Could a manufacturing mix-up be as detrimental as the fact that a drug simply doesn’t work? Nektar learned the answer the hard way with its Bristol-Myers Squibb-partnered experimental cancer therapy. On Thursday, Nektar CEO Howard Robin went to great lengths to explain why response rates dropped in the second stage of a clinical trial testing NKTR-214 (bempegaldesleukin) in tandem… Read More »

Protein-linked sugars are crucial for the uptake of proteins linked to Parkinson’s disease

Parkinson’s disease, a neurodegenerative disorder that affects more than 6 million people worldwide, is caused by the buildup of alpha-synuclein proteins in the brain. The biological function of alpha-synuclein is still not well understood, but because of its role in neurodegenerative diseases, researchers are actively studying this protein to understand the mechanisms of the disease… Read More »

Medical News Today: Key brain area plays a crucial role in addiction

New research finds that the cerebellum, a large part of the human brain that scientists thought was primarily involved in motor control, may play a key role in reward-seeking and social behaviors. The findings may help inform future therapies for treating addiction. New research suggests the brain’s cerebellum may explain addiction. Recent research has hinted… Read More »