Tag Archives: manufacturing

CDMO WuXi STA opens manufacturing facility to produce oligonucleotides 

CDMO WuXi STA is building out its manufacturing site in Changzhou, China in stages. Its newest milestone is a large-scale oligonucleotide API manufacturing unit. It says the 30,000-square-foot manufacturing facility can produce a variety of oligonucleotides including DNA, RNA, morpholino oligonucleotide (PMO) and peptide conjugates (PPMO). It can produce oligonucleotide APIs up to 1 mol… Read More »

Novartis’ new cell therapy facility could ease manufacturing squeeze for CAR-T med Kymriah

Novartis’ big push into cell and gene therapy hasn’t been the smoothest of rides, with a data manipulation scandal hamstringing Zolgensma and manufacturing concerns hurting CAR-T cancer therapy Kymriah. Could a new European facility help turn around the latter’s production bottleneck?  Novartis last week opened its newest cell and gene therapy facility in Stein, Switzerland,… Read More »

Faulty manufacturing trips up Nektar’s Bristol-partnered cancer drug in crucial trial

Could a manufacturing mix-up be as detrimental as the fact that a drug simply doesn’t work? Nektar learned the answer the hard way with its Bristol-Myers Squibb-partnered experimental cancer therapy. On Thursday, Nektar CEO Howard Robin went to great lengths to explain why response rates dropped in the second stage of a clinical trial testing NKTR-214 (bempegaldesleukin) in tandem… Read More »