All other authors: no conflicts. Aspergillus infection. Curr Hematol Malig Rep ; 11 : 19— Risk factors for recurrent fever after the discontinuation of empiric antibiotic therapy for fever and neutropenia in pediatric patients with a malignancy or hematologic condition. Once daily, oral, outpatient quinolone monotherapy for low-risk cancer patients with fever and neutropenia: a pilot study of 40 patients based on validated risk-prediction rules. High-risk patient with fever after 4 days of empirical antibiotics. Feasibility of outpatient management of fever in cancer patients with low-risk neutropenia: results of a prospective randomized trial. Diagnosis of catheter-related bloodstream infections among pediatric oncology patients lacking a peripheral culture, using differential time to detection.
As the result of an error in the publishing process, the version of the manuscript initially posted on the internet on January 4th was posted prematurely for a total of 10 hours and was not the final version. The final version, shown here, contains slight editing changes. There were no substantive changes to the content or conclusions and no changes in authorship or statements of potential conflict of interest compared to the earlier posted version. Alison G. Freifeld, Eric J. Bow, Kent A. Sepkowitz, Michael J. Boeckh, James I.
It remains true that all patients who present with fever and neutropenia should be treated swiftly and broadly with antibiotics to treat both gram-positive and gram-negative pathogens. Comparison of meropenem with amikacin plus ceftazidime in the empirical treatment of febrile neutropenia: a prospective randomised multicentre trial in patients without previous prophylactic antibiotics. The role of body mass index and other body composition parameters in early post-transplant complications in patients undergoing allogeneic stem cell transplantation with busulfan—cyclophosphamide conditioning. Lower respiratory tract specimens obtained by bronchoalveolar lavage BAL are recommended for patients with an infiltrate of uncertain etiology visible on chest imaging. Ciprofloxacin should not be employed as a solo agent because of its poor coverage of gram-positive organisms [ 12, 21, , — ]. The duration of systemic antimicrobial therapy depends on several factors, including whether the catheter was removed or retained, response to antimicrobial therapy within 48—72 h resolution of fever and bacteremia, and whether complicated infection deep tissue infection, septic thrombosis, or endocarditis [ ] is present.