All life is challenged by oxidants — reactive molecules or compounds that remove electrons from other molecules — often with adverse effect, commonly referred to as oxidative stress. Consequently, all organisms have evolved specialized antioxidant defenses. In humans and other multicellular animals, that defense depends upon a protein called NRF2 and its inhibitor, KEAP1. In… Read More »
Mark Strausman, the chef behind celebrity hot spot Freds, says he became worried about the future of luxury retailer Barneys — where Freds is housed — long before the company filed for bankruptcy in August. In an exclusive interview with Side Dish, Strausman said the problems began with the change of management that came in… Read More »
Hepatitis C-infected kidneys are safe and work as well as uninfected organs, study finds For years, most transplant centers discarded kidneys infected with hepatitis C over fears the recipients would have lower survival rates Since 2015, there are three times as many centers using infected kidneys thanks to new antiviral treatments Researchers looked at hepatitis C-infected… Read More »
Anorexia may be linked to many genetic variantsGetty images By Jessica Hamzelou Anorexia nervosa isn’t just a psychiatric condition – it is a metabolic one, too, according to a genetic study of around 72,500 people. The findings help to explain some of the symptoms of anorexia, and could help to shape future treatments. Anorexia affects… Read More »
Bristol-Myers Squibb sold $ 19 billion in bonds on Tuesday, 2019’s largest bond issue so far. (BMS) Bristol-Myers Squibb is taking on a debt load to cover its $ 74 billion Celgene buyout, and it issued $ 19 billion in bonds Tuesday to help pay the bill. Bristol-Myers issued bonds in nine tranches that come due starting… Read More »
Jeopardy! host Alex Trebek says his cancer indicators have gone down — but his well-being hasn’t necessarily improved accordingly. “My oncologist says I’m doing well even though I don’t always feel it,” Trebek said Wednesday on Good Morning America, joking that he has discovered he is “a big wuss.” Trebek, who was diagnosed this year… Read More »
Cholesterol-lowering “statin” drugs taken by millions of Britons may not work well enough in about half of those prescribed them, research suggests. UK investigators looked at 165,000 patients on statins and found that for one in two, the drugs had too little effect on bad cholesterol – one of the big risk factors for heart… Read More »